Survey of compounds which have been tested for carcinogenic activity
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Survey of compounds which have been tested for carcinogenic activity

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Published by U.S. Department of Health and Human Services in [s.l.] .
Written in English


Book details:

Edition Notes

Formerly Public health service publication no. 149.

Statementprepared for the National Cancer Institute by Technical Resources, Inc.. 1987-1988 volume. Section I.
SeriesNIH Publication No. 89-468
ContributionsNational Cancer Institute., United States. Department of Health and Human Services., National Institutes of Health.
ID Numbers
Open LibraryOL14387697M

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Survey of Compounds which have been Tested for Carcinogenic Activity. Author(s): Hartwell, J. L. Author Affiliation: Research Fellow, National Cancer Institute, National Institute of Health, United States Public Health by: Survey of Compounds which have been tested for Carcinogenic Activity. The book consists, apart from a 3-page introduction, The proportion of new compounds shown as exhibiting carcinogenic potency-1 in 4 of those tested-is identical with that noted in the first by: Research included dates from through , made this the largest database on this topic in the world. The PHS- Series has been used as a major information tool. The database contained 13 volumes with data on 7, chemical substances for which long term bioassays have been performed. Survey of compounds which have been tested for carcinogenic activity.

No attempt was made to standardize abbreviations; they should, however, be meaningful to the reader when taken in context. It is, therefore, of paramount importance that this survey not be used as a . Survey of compounds which have been tested for carcinogenic activity. Imprint [Washington]: Federal Security Agency, U.S. Public Health Service, Library has: , /, /, /, // Carcinogens > Periodicals. Bibliographic information. Beginning date Frequency. Of the ap- proximately compounds in this Supplement which are found to induce tumors, are new while 30 were re- ported as negative in the last edition of the “Survey”. It can be seen that the proportion of carcinogens among the new compounds (21%) is similar to that found before (23%). Survey of compounds which have been tested for carcinogenic activity. Rockville, Md., Title from vols. issued out of chronological ed. covers compounds surveyed through ; 2nd ed. covers through ; suppl. 1 covers ; suppl. 2 covers Vols. for issued in ed Author: National Cancer Institute (U.S.).

This is a pamphlet bound in paper and printed by the offset process, presumably for distribution by the United States Public Health Service. The title describes the contents. It is a bibliography of practically all the important compounds which have been tested as carcinogenic agents. It does not. The work of Ames and colleagues1,71,73 has led to development of microbial mutation assays to detect chemical carcinogens. Originally, analyses with the Salmonella/microsome test were inductive; known animal carcinogens were tested for mutagenic activity for validation purposes. However, testing strategies have evolved, and short-term mutagenicity tests are now used to screen for chemicals. P. Shubik and J.L. Hartwell, “Survey o f Compounds Which Have Been Tested for Carcinogenic Activity,” Suppl. 1, U.S. Public Health Service, Publ. , Washington, D.C, 6. In addition, Hartwell () has published a Survey of Compounds Which Have Been Tested for Carcinogenic Activity. II. Historical 1. Polycyclic Aromatic Hydrocarbons Soot, coal tar, shale oil, and some other complex industrial materials have long been known to Cited by: